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ITT manufactures a tank bottom valve, machined from solid 316-L or alloys if requested. Easy and trouble free weldable in vessel bottoms. The ITT TBV is designed for hygienic application and is easy cleanable.
Anderson-Negele website 
Diaphragms 
Millipore NovAseptic tankbottom valves are designed for this application, it is very easy to mount a steamport. Valves are available with hand- and pneumatically operated bonnets.